Interaction between Infections and Diabetes (English)
A public health seminar lecture delivered on February 6, 2012 by Dr. Christie Jeong.
The theory of Epidemiological Transition argues that as a population develops, mortality due to infectious diseases decreases with a simultaneous rise in 'man-made' chronic diseases. This perspective has oversimplified the current reality in which prevalence of chronic diseases has been increasing in populations in whom infectious diseases have not been optimally controlled. For instance, diabetes has been increasing in areas with yet a high burden of tuberculosis. This is a concern given that uncontrolled diabetes leads to greater vulnerability to infections such as tuberculosis. Further, there has been growing evidence that infections may play a role in the progression of chronic diseases. Gut microbes, for example, have been implicated in the pathogenesis of metabolic syndrome. While the dual burden of infections and diabetes poses a challenge for public health, it also creates an opportunity for productive interdisciplinary collaboration, and novel discoveries.