Chem 128. Lec. 04. Intro to Chemical Biology. Combinatorial Chemistry and Biology (English)


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UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Lec 04. Introduction to Chemical Biology -- Combinatorial Chemistry and Biology
View the complete course: http://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html
Instructor: Gregory Weiss, Ph.D.


License: Creative Commons BY-NC-SA
Terms of Use: http://ocw.uci.edu/info.
More courses at http://ocw.uci.edu


Description: This video is part of a 18-lecture undergraduate-level course titled "Introduction to Chemical Biology" taught at UC Irvine by Professor Gregory Weiss. Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Introduction to Chemical Biology (Chem 128) is part of OpenChem: http://ocw.uci.edu/openchem


Recorded on January 17, 2013.


Index of Topics:
Announcements
0:00:58 - Week 2 Overview
0:03:19 - Announcements
0:05:04 - Journal Article Report Example

Lecture:
0:28:06 - Our Story To Date on Thursday
0:32:32 - Do Not Use Curved Arrows for Hydrogen Bonds
0:34:00 - The Molecules of Life on Earth
0:34:50 - Ingredients in the Recipe of Life
0:36:32 - Building the Building Blocks of Life
0:37:40 - Chemistry of HCN
0:39:06 - HCN=The Chemistry of Life
0:39:50 - White Board Example
0:50:27 - Formation of DAMN
0:50:40 - Formation of AICN
0:53:32 - Prebiotic Sythesis of Pyrimidine
0:54:57 - Prebiotic Synthesis of D-Ribose from CH2O
0:55:50 - The Benzoin Reaction
0:56:40 - White Board Example or Ribose Rings
1:05:28 - Prebiotic Synthesis of D-Ribose from CH2O
1:06:29 - Oligomers of Nucleotide Subunits
1:08:00 -  The RNA World
1:09:19 - Prebiotic Synthesis of Amino Acids
1:10:27 - Strecker Synthesis of Amino Acids
1:11:10 - Formation of Proteins from Amino Acids
1:11:29 - Non-Covalent Interactions Control All Biology
1:12:35 - Non-Covalent Interactions Dominate Biology
1:13:21 - A Spectrum of Bonding
1:14:34 - Non-Covalent Bonding Equation
1:16:35 - Charge-Charge Interactions
1:18:19 - Caution! Formal Charges are Not the Same as Partial Charges


Required attribution: Weiss, Gregory Introduction to Chemical Biology 128 (UCI OpenCourseWare: University of California, Irvine),  http://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html. [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License.


Author:
Gregory Alan Weiss
Title:
Professor
Department:
Chemistry
Creative Commons License
Chem 128: Intro to Chemical Biology. Lecture 4: Combinatorial Chemistry and Biology by Gregory Weiss is licensed under a Creative Commons Attribution-ShareAlike 3.0 Unported License.
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